Strength is a key aspect of athletic performance, and anabolic steroids have long been associated with enhancing this attribute. Anabolic steroids are synthetic variations of the male hormone testosterone, and they work by increasing protein synthesis within the body. This leads to accelerated muscle growth and improved recovery, which can ultimately result in enhanced strength.
When individuals use anabolic steroids, they often experience significant increases in muscle mass and power. This is due to the steroid's ability to stimulate the muscles to retain more nitrogen, leading to increased protein synthesis. As a result, athletes may witness substantial gains in their strength levels, allowing them to lift heavier weights and perform better in their respective sports.
It is important to note, however, that the use of anabolic steroids for strength enhancement is not without risks. Prolonged steroid use can have detrimental effects on overall health, including liver damage, cardiovascular issues, hormonal imbalances, and psychological side effects. Additionally, the use of steroids is often considered unethical and is banned in most competitive sports due to its unfair advantage.
In summary, anabolic steroids have been historically linked to improved strength by promoting muscle growth and protein synthesis. While they can provide short-term benefits, it is crucial to weigh the potential risks and consider the ethical implications associated with their use.
Nolvadex is a popular and powerfully effective Selective Estrogen Receptor Modulator (SERM) that is often referred to as an anti-estrogen. However, while being an antagonist it is also an agonist as it will actually act as estrogen in certain parts of the body while acting as an anti-estrogen in other areas. As one of the oldest SERM’s on the market that is still regularly used medicinally, while Nolvadex is also used by anabolic steroid users it is not an anabolic steroid. This is an important note as some are often confused by its use in steroid cycles. Nolvadex is simply a SERM. Nolvadex, officially known as Tamoxifen Citrate, was first developed in 1961 by ICI now AstraZeneca under the trade name Nolvadex. The SERM was developed to treat breast cancer, specifically hormone-responsive breast cancer. However, it has also been effectively used in breast cancer prevention. Then we have anabolic steroid users, and it was long ago discovered that Nolvadex had a place among such individuals. Nolva, as it’s commonly known, can be used as an anti-estrogen during an anabolic steroid cycle in order to prevent estrogenic related side effects. It is also used as part of a Post Cycle Therapy (PCT) recovery plan, which is its most common and beneficial point of use for the steroid user.
Nolvadex Functions & Traits:
Tamoxifen Citrate is a SERM with both estrogen agonist and antagonist properties. As an anti-estrogen, Nolvadex functions by binding to the estrogen receptors in the place of estrogen. This binding prevents the estrogen hormone from performing its action in certain parts of the body, which is precisely why it’s beneficial to breast cancer patients. Many forms of breast cancer actually feed off estrogen when it attaches to the receptors in the chest. By preventing the attachment in such receptors, this also protects anabolic steroid users from gynecomastia, which can be caused by anabolic steroids that aromatize such as Testosterone, Dianabol, and Nandrolone and Boldenone to a degree. While primarily viewed as an anti-estrogen, Nolvadex also has the ability to act as estrogen, specifically in the liver. This presents a benefit as estrogenic activity in the liver has been linked to healthier cholesterol levels. For the steroid user, this can be extremely beneficial as many anabolic steroids tend to have an adverse effect on cholesterol. More on this when we look at the direct effects of Nolvadex later on. Although primarily an anti-estrogen, Nolvadex also possess strong testosterone stimulating characteristics. Nolvadex has the ability to block the negative feedback that is brought on by estrogen at the hypothalamus and pituitary. As a result, this stimulates an enhanced release by the pituitary of Luteinizing Hormone (LH) and Follicle Stimulating Hormone (FSH). Both LH and FSH are essential to natural testosterone production. Without LH and FSH, with an even stronger emphasis on LH, there is no natural testosterone production.
Effects of Nolvadex:
For the breast cancer patient, the effects of Nolvadex are very straightforward. By blocking the estrogen hormone from attaching the cancer is unable to feed on the hormone necessary to its survival. While effective, it’s not always the only compound used or even the first. Often Aromatase Inhibitors (AI’s) are used early on as they have the ability to lower serum estrogen levels. In time, a switch from an AI to a SERM like Nolvadex will be made. In a preventative situation, those who have a strong family history of breast cancer may prevent it by Nolvadex use early on. For the anabolic steroid user, the primary effect of Nolvadex on cycle is in the prevention of gynecomastia. Nolvadex does not appear to have a strong effect in preventing the other primary estrogenic effect in water retention, but this can often be controlled in other ways. As for gynecomastia protection, this can be enough for many men and should be your first choice if it can get the job done. If not, you will need an AI like Arimidex (Anastrozole) or Femara (Letrozole). However, AI’s can have a negative effect on cholesterol. Alone AI’s do not appear to have a strong, negative effect, but when coupled with an aromatizing steroid this effect appears to be exasperated. Cholesterol can be controlled with the use of an AI, but if it can get the job done a SERM like Nolvadex should be your first choice. As an added bonus, remember this SERM will have a positive impact on your cholesterol levels. The final effect of Nolvadex represents the most valuable one for the anabolic steroid user. The use of anabolic steroids will suppress natural testosterone production. The rate of suppression will be dependent on the steroid(s) being used, but in most cases, it will be significant. Once the use of anabolic steroids comes to an end, assuming the individual did not suffer from a prior low testosterone condition and did not damage his Hypothalamic-Pituitary-Testicular-Axis (HPTA) through improper practices, natural testosterone production will begin again. This natural production will begin on its own, however, there is a problem. Once you come off cycle your natural testosterone levels will be extremely low and while production will begin again they will remain low for a very long time. It will take months and months for the body to fully recover its prior high natural testosterone levels. In fact, it could take up to a year or more depending on the harshness of the cycle and the individual’s general dispositions. This means the individual will be in a state of low testosterone for quite some time, and that can come with a host of bothersome symptoms. This condition can include all the symptoms associated with low testosterone. Further, with testosterone levels low, the individual may very well lose a lot of muscle tissue gained through steroid use as cortisol becomes the dominant hormone in the body. Due to the low testosterone issues after a cycle of anabolic steroids, most men are encouraged to implement a PCT plan that includes Nolvadex post anabolic steroid use. Solid PCT plans often contain Nolvadex as well as the SERM Clomid (Clomiphene Citrate) and the powerful peptide hormone HCG (Human Chorionic Gonadotropin). By implementing this PCT plan, you will greatly stimulate natural testosterone production, speed up the recovery process and greatly protect your physique. Once the PCT plan comes to an end, contrary to popular belief your testosterone levels will not be resting at their normal high level state. Total recovery will still take a lot of time. However, a PCT plan that includes Nolvadex will ensure you have enough testosterone for proper bodily function while your levels continue to naturally rise. There are many performance enhancing athletes that scoff at PCT plans, and there is a time to forgo them. If you’re only going to be off cycle for a short period of time, say 4-6 weeks or are cruising on a low testosterone dose between full blown cycles, there is no logical reason for a PCT plan. Such scenarios are very common in hardcore bodybuilding circles but they are not realistic for most anabolic steroid users. Most steroid users will take a fair amount of time off cycle, and in the name of health and wellbeing this is the best approach. If this is the case, there is no logical reason for forgoing PCT, and we can guarantee those that implement it will be far better off.
Side Effects of Nolvadex:
There are possible side effects of Nolvadex use, but we will find this is a very well-tolerated SERM for most men and women. However, there are possible side effects but they are generally very rare. Most men will not have the first problem. The side effects of Nolvadex will be a little more common in women but even then they are not all that common. The possible side effects of Nolvadex use include:
Vaginal Itching, bleeding, discharge or discomfort
Hot Flashes
Upset Stomach
Headaches
The above are the most common side effects of Nolvadex. Other possible side effects of Nolvadex although less common than above include:
Rash
Decreased White Blood Cell Count
Endometrial Changes
Increased Triglyceride Levels
Pulmonary Embolism
When it comes to the side effects of Nolvadex that really is all there is to it. Undoubtedly some of those effects do not sound all that pleasant, but again, most all the side effects of Nolvadex are fairly rare. As a final note, women who are pregnant or who may become pregnant should not for any reason take Nolvadex. Such use can potentially be very damaging to the developing child.
Supra-Testosterone 400, also known as Sustanon 400, is a popular anabolic steroid that is widely used by bodybuilders and athletes. It is a testosterone blend that contains four different esterified testosterone compounds, making it a powerful and versatile performance-enhancing drug.
The four testosterone esters present in Supra-Testosterone 400 are testosterone propionate, testosterone phenylpropionate, testosterone isocaproate, and testosterone decanoate. Each ester has a different release time, which results in a sustained and prolonged release of testosterone into the bloodstream.
The main purpose of using Supra-Testosterone 400 is to increase testosterone levels in the body. Testosterone is a naturally occurring hormone in both men and women, but it is predominantly a male sex hormone. It plays a crucial role in muscle growth, strength, libido, bone density, and overall well-being.
By using Supra-Testosterone 400, individuals can experience several benefits. Firstly, it enhances protein synthesis, which leads to an increase in muscle mass and strength. This makes it an ideal choice for bodybuilders and athletes looking to improve their performance and physique.
Additionally, Supra-Testosterone 400 can boost red blood cell production, resulting in improved oxygen-carrying capacity. This can enhance endurance and stamina, allowing athletes to train harder and recover faster.
Supra-Testosterone 400 also promotes nitrogen retention, which is essential for muscle growth and recovery. It helps to prevent muscle breakdown and catabolism, allowing users to maintain muscle mass during intense training or cutting phases.
It is important to note that Supra-Testosterone 400 is a potent steroid and should be used with caution. It is typically administered through intramuscular injection, and the dosage and frequency of administration depend on individual goals, experience, and tolerance.
Like any anabolic steroid, Supra-Testosterone 400 can have potential side effects. These may include acne, oily skin, hair loss, increased aggression, mood swings, and suppression of natural testosterone production. It is crucial to follow proper dosage guidelines, have regular blood tests, and consult with a healthcare professional before beginning any steroid cycle.
In conclusion, Supra-Testosterone 400 (Sustanon 400) is a powerful testosterone blend that is commonly used by bodybuilders and athletes to enhance muscle growth, strength, and performance. It provides a sustained release of testosterone into the body, resulting in various beneficial effects. However, it should be used responsibly and under professional supervision to minimize the risk of side effects.
**MOTs-C Peptides: A Detailed Description**
MOTs-C (Mitochondrial Open Reading Frame of the 12S rRNA Type-C) peptides are a newly discovered class of small signaling molecules that have gained significant attention in the field of aging and longevity research. These peptides are derived from a specific region of the mitochondrial genome and have shown promising effects on various aspects of health and lifespan.
Mitochondria, often referred to as the "powerhouses" of cells, are responsible for generating energy in the form of adenosine triphosphate (ATP). As we age, mitochondrial function tends to decline, leading to a decrease in energy production and an increase in oxidative stress. This decline in mitochondrial function has been linked to various age-related diseases and the overall aging process.
MOTs-C peptides are believed to play a crucial role in maintaining mitochondrial health and function. Research has shown that these peptides can help improve mitochondrial respiration, enhance ATP production, and reduce oxidative stress. By doing so, MOTs-C peptides may have the potential to slow down the aging process and promote overall health and longevity.
Studies conducted on animal models and human cells have demonstrated several beneficial effects of MOTs-C peptides. One of the key findings is their ability to activate AMP-activated protein kinase (AMPK), a cellular energy sensor that regulates metabolism and promotes cellular homeostasis. Activation of AMPK has been associated with various health benefits, including improved insulin sensitivity, enhanced mitochondrial function, and increased lifespan.
Furthermore, MOTs-C peptides have shown anti-inflammatory properties by inhibiting the activation of nuclear factor kappa B (NF-κB), a key regulator of the inflammatory response. Chronic inflammation is a hallmark of aging and is closely linked to the development of age-related diseases such as cardiovascular disease, neurodegenerative disorders, and cancer. By reducing inflammation, MOTs-C peptides may help mitigate age-related inflammation and its associated health risks.
In addition to their effects on energy production and inflammation, MOTs-C peptides have been shown to enhance cellular stress resistance. They can activate cellular pathways involved in stress response, such as the NRF2 (nuclear factor erythroid 2-related factor 2) pathway, which plays a crucial role in antioxidant defense and detoxification. By activating these pathways, MOTs-C peptides may help protect cells from oxidative damage and enhance their ability to cope with stressors.
Although research on MOTs-C peptides is still in its early stages, the potential implications for human health and aging are exciting. Further studies are needed to fully understand the mechanisms of action, optimal dosage, and potential side effects of these peptides. However, the preliminary findings suggest that MOTs-C peptides hold promise as a potential therapeutic intervention for age-related diseases and the promotion of healthy aging.
It is important to note that MOTs-C peptides are currently being investigated in preclinical and early clinical trials, and they are not yet widely available as approved treatments. As with any emerging therapy, it is essential to exercise caution and consult with healthcare professionals before considering the use of MOTs-C peptides.
Nandrolone phenylpropionate, also known as NPP, is an anabolic androgenic steroid (AAS) that belongs to the family of nandrolone compounds. It is a modified form of testosterone with an attached phenylpropionate ester, which alters its pharmacokinetics and provides a shorter half-life compared to other nandrolone esters.
NPP is primarily used in the medical field for various therapeutic purposes. It has been prescribed to treat conditions such as osteoporosis, muscle wasting diseases, and certain forms of anemia. Additionally, it has been used to enhance recovery from injuries and surgeries, aiding in the regeneration and repair of tissues.
From a performance-enhancing perspective, NPP is popular among bodybuilders and athletes due to its ability to promote muscle growth and enhance physical performance. It exhibits strong anabolic properties while having a relatively lower androgenic effect compared to testosterone, making it a favorable choice for those seeking gains in lean muscle mass without excessive androgenic side effects.
NPP works by binding to androgen receptors in the body, stimulating protein synthesis and nitrogen retention, which are essential for muscle growth and recovery. It also increases the production of red blood cells, improving oxygen-carrying capacity and endurance. These effects contribute to enhanced strength, increased muscle size, and improved athletic performance.
As with any AAS, NPP carries potential side effects. Some common androgenic side effects include oily skin, acne, and increased facial or body hair growth. It can also suppress natural testosterone production, leading to temporary infertility or testicular atrophy. Additionally, it may cause cardiovascular issues, such as increased cholesterol levels and high blood pressure, and can have adverse effects on liver function.
Proper administration and dosage are essential to minimizing the risks associated with NPP. It is typically administered through intramuscular injections, with dosages ranging from 50mg to 100mg every other day or every three days. The duration of NPP cycles can vary, typically lasting between 6 to 12 weeks.
It is important to note that the use of NPP, or any other AAS, without proper medical supervision is considered illegal and potentially dangerous. Misuse or abuse of these substances can result in serious health consequences and may violate anti-doping regulations in sports.
If you are considering using NPP or any other AAS, it is crucial to consult with a qualified healthcare professional who can provide guidance, monitor your health, and ensure your safety throughout the process.
Follistatin is a single-chain gonadal protein that specifically inhibits follicle-stimulating hormone release. The single FST gene encodes two isoforms, FST317 and FST344 containing 317 and 344 amino acids respectively, resulting from alternative splicing of the precursor mRNAFollistatin binds directly to activin and functions as an activin antagonist. specific inhibitor of the biosynthesis and secretion of pituitary follicle stimulating hormone (fsh).
Follistatin is being studied for its role in regulation of muscle growth in mice, as an antagonist to myostatin (also known as GDF-8, a TGF superfamily member) which inhibits excessive muscle growth. Lee & McPherron demonstrated that inhibition of GDF-8, either by genetic elimination (knockout mice) or by increasing the amount of follistatin, resulted in greatly increased muscle mass. In 2009, research with macaque monkeys demonstrated that regulating follistatin via gene therapy also resulted in muscle growth and increases in strength.
Chemical name: (17β)-3-Oxoestra-4,9,11-tried-17-yl acetate
Formula: C20H24O3
Anabolic activity index: 500%
Androgenic activity index: 500%
TRENBOLONE ENANTHATE 400mg
1 vial x 10ml, 400 mg/ml
Carrier: MCT Oil
Trenbolone Enanthate – is an injectable steroid that is used mainly in bodybuilding and weightlifting to achieve maximum growth of compacted muscle mass and a significant increase in power capacity.
Trenbolone Enanthate ester is characterized by a long period of exposure to the body (about six weeks).
Trenbolone Enanthate Effects
significant increase in muscle mass (average 10 kg per 8 weeks);
increasing the degree of endurance and power performance;
200% increase in the level of insulin-like growth factor stimulation and hyperplasia of the muscle;
fat burning effect (including the influence due to the release of growth hormone);
lowering cortisol levels (a hormone that facilitates the destruction of proteins, increased fat accumulation, and glucose).
How to Use Trenbolone Enanthate: Dosage, Cycle, PCT
To create a cycle for Trenbolone Enanthate, which also would be effective and safe for the body, stick to a few rules:
Do not exceed the dosage of the drug and duration of the cycle (the optimal dose of Trenbolone Enanthate per week – is 300 mg, and cycle length – is 6-8 weeks).
Always start with a minimum rate of injection to fix the body’s response to anabolic effects.
Take Gonadotropins, if the steroid cycle is designed for 5 weeks and more.
Do not neglect the power of sports complex and a special diet for weight gain.
Always consult a doctor before starting the cycle.
Trenbolone Enanthate Combination Cycles
Trenbolone Enanthate, to gain muscle mass, is often taken solo, because of its efficiency. In professional cycles, a dosage of 250 mg per week, can be stacked with Testosterone Enanthate, but this combination is only valid for experienced athletes and after medical advice.
For the drying period, one can buy Winstrol, or Anavar without anti-estrogens, using half of the dosage.
As PCT on Trenbolone cycle is used Toremifene or Clomid.
Trenbolone Enanthate Reviews
After analyzing published Trenbolone Enanthate reviews, it is easy to conclude the quality of weight and severity of the effect: more than 90% of athletes and bodybuilders were satisfied with the results of the cycle. The absence of the phenomenon of rollback and flavoring also played a significant role in athletes with this steroid.
Warnings: Keep out of reach of children. For adults only.
GW501516 10 (Cardarine) 100 TABS
ACTIVE HALF-LIFE 20-24 hours CLASSIFICATION PPAR-delta agonist DOSAGE 20 mg/day ACNE WATER RETENTION HBR HEPATOTOXICITY AROMATIZATION MANUFACTURER, RX pharmaceutical SUBSTANCE,CARDARINE
In spite of the fact that many consider cardarine (GW 501516) to be a SARM, it is technically a PPAR-delta agonist (peroxisome proliferator-activated receptors). In fact, it is usually sold as a SARM, just like a tomato being a fruit is always sold as a vegetable. Cardarine was developed for health benefits, and it works by activating the same pathways that the body activates when we exercise. In this article we will discuss everything you need to know about this potent drug in plain English.
Cardarine was discovered as a result of GSK and Ligand Pharma research collaborations that started in the early 1990’s. Interestingly, the compound reached phase 1 trials in 2000 for treatment of lipid strain, and then, it was discontinued in 2008. Nonetheless, today, it is used as a research compound, whilst athletes use it for performance enhancing and fat burning purposes.
Medical Uses
Cardarine was primarily developed to treat obesity, diabetes, lipid strain, and heart health problems. As a matter of fact, those who run blood work will notice that cardarine will magically aid with lipid strain, and their cholesterol levels will improve substantially.
Athletic Uses
Cardarine is used by athletes competing in many different sports. For instance, endurance athletes may increase exercise endurance by stacking this PPAR with the AMP analog drug AICAR, or run cardarine solo. As a result, they will have a greater ability to reach higher RPM’s during their runs without hitting the maximum heart rate. This will allow the runner/cyclist/swimmer to cheat their maximum heart rates and go longer without getting winded, making this stack an incredible weapon to use in endurance sports. Actually, from personal experience I can tell that cardarine can knock over 30-45 seconds off a 5K time if used leading up to a race.
Regarding the bodybuilders, cardarine can benefit them in two ways:
1. Its ability to burn fat
2. Its ability to help the athlete have harder and longer workouts, without getting winded.
When a lifter does a set, their heart rate will skyrocket, and many times the athlete will reach failure slower when on cardarine because they can get in that extra rep or two. Furthermore, you will need less rest periods in between sets, and bodybuilders who like to do cardio after their weight training will enjoy these benefits as well.
Doping
Cardarine was heavily abused by numerous athletes ahead of the 2008 Beijing Olympic Games and was banned by WADA in 2009, which categorized it as a ‘hormone and metabolic modulator.‘
Moreover, numerous cyclists have been busted for using cardarine; Russian cyclist Valery Kaykov was suspended, and in 2013 Miguel Ubeto from Venezuela was kicked off the Lampre team. In fact, last year, Elena Lashmanova of Russia, the world record holder in the 20M race walk, tested positive for cardarine.
Fat loss
In terms of obesity, cardarine reverses metabolic abnormalities in obese and pre-diabetic men by stimulating fatty acid oxidation. That is, it burns fat by increasing glucose uptake in skeletal muscle tissue, which changes the body’s metabolism to burn fat for energy instead of muscle or carbs. Incredibly, it does all this without dropping blood sugar levels like diabetic drugs do. Interestingly, when mice were given a high fat diet, they still lost fat, which proves that cardarine prevents obesity.
Stacking
There are a few ways to stack cardarine:
1. Endurance: I recommend stacking cardarine with AICAR and/or Equipoise. This is the ultimate endurance stack that will turn you into a race horse.
2. Fat loss: The best shredder stack would be stacking cardarine with S4 (Andarine). This is a well known potent ‘cutting’ stack.
3. Anabolic steroid stack: If you run moderate doses of anabolic steroids, or you run any harsh compound like trenbolone, then cardarine will aid in not only your lipids, but also with your ability to ‘catch your wind.’ Therefore, cardarine is a perfect stack for trenbolone, which makes many athletes lose their breath fast.
4. During PCT (post cycle therapy) or bridge: Since cardarine is not hormonal, it is in no way suppressive. Hence, you should not be scared of using it to keep fat off and improve your workouts between cycles during your bridge and PCT.
5. SARMs triple stack: If you want to recomp, cardarine stacks beautifully with S4 and MK-2866.
Side Effects
Side effects are rare with cardarine, but like with all drugs, it should be run under the correct dosage and be cycled on and off. Due to the fact that it is not a hormone there is no need to worry about PCT or suppression.
Half life, use and dosage
The normal dose for both men and women are 20 milligrams (mg) per day.
The half life of GW501516 is 20-24 hours. This means that once a day dose is totally fine. Some athletes like to use all the 20 mg an hour before their workout session, and others will split the dose in half in the AM and PM.
It is best to squirt the liquid into your mouth, swallow, and then chase down with some juice or water.
Cypo-Testosterone, also known as Testosterone Cypionate, is a synthetic form of testosterone, which is the primary male sex hormone. It is widely used in medical settings and by athletes for various purposes. Testosterone Cypionate is available in the form of an injectable solution with a concentration of 250mg/ml.
Testosterone Cypionate is prescribed by doctors to treat conditions caused by low testosterone levels in males, such as hypogonadism. It helps to restore testosterone levels to a normal range and alleviate symptoms like fatigue, reduced libido, muscle loss, and mood changes. It is usually administered through intramuscular injections.
In the field of sports and bodybuilding, Testosterone Cypionate is commonly used as an anabolic steroid. It is highly effective in promoting muscle growth, enhancing strength, and improving athletic performance. Athletes and bodybuilders often utilize it during bulking cycles to gain muscle mass and increase power. Additionally, it can also be used during cutting cycles to preserve muscle mass while reducing body fat.
The recommended dosage of Testosterone Cypionate can vary depending on the individual's needs and medical condition. For medical treatment, the typical dosage ranges from 50mg to 400mg every two to four weeks. In the case of performance enhancement, dosages can be higher, often ranging from 200mg to 800mg per week. However, it is important to note that such usage is illegal and carries potential risks.
As with any medication or anabolic steroid, Testosterone Cypionate may have side effects. These can include acne, oily skin, water retention, gynecomastia (enlarged breast tissue in males), increased body hair growth, and changes in mood. It can also suppress natural testosterone production, so a post-cycle therapy (PCT) is often recommended after a cycle to help restore hormone balance.
It is crucial to use Testosterone Cypionate responsibly and under the guidance of a healthcare professional. Misuse or abuse of this substance can lead to serious health consequences. Additionally, it is important to be aware of the legal implications surrounding the use of anabolic steroids, as regulations vary from country to country.